Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
5902 results
Journal of vascular surgery, Volume 79, Issue 6, 1 1 2024, Pages 1539-1540 Reply. Willems SA, van der Vorst JR, Brouwers JJWM
Diabetes care, Volume 47, Issue 6, 1 1 2024, Pages 1042-1047 Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes. Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). Research design and methods: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. Results: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18.2%). We identified three novel genetic loc... Abstract
ESC heart failure, 22 4 2024 In vivo fluid dynamics of the Ventura interatrial shunt device in patients with heart failure. Pfeiffer M, Boehmer J, Gorcsan J, Eguchi S, Orihara Y, Perl ML, Eigler N, Abraham WT, Villota JN, Lee E, Bayés-Genís A, Moravsky G, Kar S, Zile MR, Holcomb R, Anker SD, Stone GW, Rodés-Cabau J, Lindenfeld J, Bax JJ
Aims: Interatrial shunts are under evaluation as a treatment for heart failure (HF); however, their in vivo flow performance has not been quantitatively studied. We aimed to investigate the fluid dynamics properties of the 0.51 cm orifice diameter Ventura shunt and assess its lumen integrity with serial transesophageal echocardiography (TEE). Methods and results: Computational fluid dynamics (CFD) and bench flow tests were used to establish the flow-pressure relationship of the shunt. Open-label... Abstract
Nature ecology & evolution, 20 3 2024 Directed conservation of the world's reef sharks and rays. Goetze JS, Heithaus MR, MacNeil MA, Harvey E, Simpfendorfer CA, Heupel MR, Meekan M, Wilson S, Bond ME, Speed CW, Currey-Randall LM, Fisher R, Sherman CS, Kiszka JJ, Rees MJ, Udyawer V, Flowers KI, Clementi GM, Asher J, Beaufort O, Bernard ATF, Berumen ML, Bierwagen SL, Boslogo T, Brooks EJ, Brown JJ, Buddo D, Cáceres C, Casareto S, Charloo V, Cinner JE, Clua EEG, Cochran JEM, Cook N, D'Alberto BM, de Graaf M, Dornhege-Lazaroff MC, Fanovich L, Farabaugh NF, Fernando D, Ferreira CEL, Fields CYA, Flam AL, Floros C, Fourqurean V, Barcia LG, Garla R, Gastrich K, George L, Graham R, Hagan V, Hardenstine RS, Heck SM, Heithaus P, Henderson AC, Hertler H, Hueter RE, Johnson M, Jupiter SD, Kaimuddin M, Kasana D, Kelley M, Kessel ST, Kiilu B, Kyne F, Langlois T, Lawe J, Lédée EJI, Lindfield S, Maggs JQ, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Newman SJ, O'Shea OR, Osuka KE, Papastamatiou YP, Perera N, Peterson BJ, Pina-Amargós F, Ponzo A, Prasetyo A, Quam
Many shark populations are in decline around the world, with severe ecological and economic consequences. Fisheries management and marine protected areas (MPAs) have both been heralded as solutions. However, the effectiveness of MPAs alone is questionable, particularly for globally threatened sharks and rays ('elasmobranchs'), with little known about how fisheries management and MPAs interact to conserve these species. Here we use a dedicated global survey of coral reef elasmobranchs t... Abstract
ESC heart failure, 16 3 2024 Cardiac amyloidosis is not a single disease: a multiparametric comparison between the light chain and transthyretin forms. Neculae G, Adam R, Jercan A, Bădeliță S, Tjahjadi C, Draghici M, Stan C, Bax JJ, Popescu BA, Marsan NA, Coriu D, Jurcuț R
Aims: Systemic amyloidosis represents a heterogeneous group of diseases resulting from amyloid fibre deposition. The purpose of this study is to establish a differential diagnosis algorithm targeted towards the two most frequent subtypes of CA. Methods and results: We prospectively included all consecutive patients with ATTR and AL evaluated between 2018 and 2022 in two centres in a score derivation cohort and a different validation sample. All patients had a complete clinical, biomarker, electr... Abstract
Clinics (Sao Paulo, Brazil), Volume 79, 16 3 2024, Pages 100382 The decline in postural balance has a negative impact on the performance of functional tasks in individuals with Parkinson's Disease. Luna NMS, Bobbio TG, de Graaf M, Greve JMD, Ernandes RC, Dias AS, Lino MHDS, Soares-Junior JM, Baracat EC, Mochizuki L, Brech GC, Alonso AC
Introduction: An accurate assessment of balance problems is critical for decreasing the risk of falling in patients with Parkinson's Disease (PD). Reliable diagnostic tools such as Computerized Dynamic Posturography (CDP) are not feasible for the clinical setting. Therefore, the present study's aim was to assess the correlation between the clinical Balance Evaluation Systems Test (BESTest) and CDP. Methods: 20 male older adults with Parkinson's Disease (PD) were included in this s... Abstract
European heart journal, 15 3 2024, Pages ehae268 Three-dimensional cardiac magnetic resonance allows the identification of slow-conducting anatomical isthmuses in tetralogy of Fallot. Kimura Y, Wallet J, Bouyer B, Jongbloed MRM, Bertels R, Hazekamp MG, Thambo JB, Iriart X, Cochet H, Sacher F, Lamb HJ, Blom NA, Zeppenfeld K
Background and aims: Patients with repaired tetralogy of Fallot remain at risk of life-threatening ventricular tachycardia related to slow-conducting anatomical isthmuses (SCAIs). Preventive ablation of SCAI identified by invasive electroanatomical mapping is increasingly performed. This study aimed to non-invasively identify SCAI using 3D late gadolinium enhancement cardiac magnetic resonance (3D-LGE-CMR). Methods: Consecutive tetralogy of Fallot patients who underwent right ventricular electro... Abstract
JACC. Cardiovascular imaging, 15 3 2024, Pages S1936-878X(24)00130-X Artificial Intelligence-Enabled Quantitative Coronary Plaque and Hemodynamic Analysis for Predicting Acute Coronary Syndrome. Koo BK, Yang S, Jung JW, Zhang J, Lee K, Hwang D, Lee KS, Doh JH, Nam CW, Kim TH, Shin ES, Chun EJ, Choi SY, Kim HK, Hong YJ, Park HJ, Kim SY, Husic M, Lambrechtsen J, Jensen JM, Nørgaard BL, Andreini D, Maurovich-Horvat P, Merkely B, Penicka M, de Bruyne B, Ihdayhid A, Ko B, Tzimas G, Leipsic J, Sanz J, Rabbat MG, Katchi F, Shah M, Tanaka N, Nakazato R, Asano T, Terashima M, Takashima H, Amano T, Sobue Y, Matsuo H, Otake H, Kubo T, Takahata M, Akasaka T, Kido T, Mochizuki T, Yokoi H, Okonogi T, Kawasaki T, Nakao K, Sakamoto T, Yonetsu T, Kakuta T, Yamauchi Y, Bax JJ, Shaw LJ, Stone PH, Narula J
Background: A lesion-level risk prediction for acute coronary syndrome (ACS) needs better characterization. Objectives: This study sought to investigate the additive value of artificial intelligence-enabled quantitative coronary plaque and hemodynamic analysis (AI-QCPHA). Methods: Among ACS patients who underwent coronary computed tomography angiography (CTA) from 1 month to 3 years before the ACS event, culprit and nonculprit lesions on coronary CTA were adjudicated based on invasive coronary a... Abstract
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 14 2 2024 Validation of a prediction model for early reconnection after cryoballoon ablation. van Waaij K, Keçe F, de Riva M, Alizadeh Dehnavi R, Wijnmaalen AP, Piers SRD, Mertens BJ, Zeppenfeld K, Trines SA
Background: We previously developed an early reconnection/dormant conduction (ERC) prediction model for cryoballoon ablation to avoid a 30-min waiting period with adenosine infusion. We now aimed to validate this model based on time to isolation, number of unsuccessful cryo-applications, and nadir balloon temperature. Methods: Consecutive atrial fibrillation patients who underwent their first cryoballoon ablation in 2018-2019 at the Leiden University Medical Center were included. Model performan... Abstract
European heart journal, 14 2 2024, Pages ehae246 Arrhythmic risk in young women with mitral valve prolapse: keep your eyes open but don't jump at every shadow. Zeppenfeld K, de Riva M
European heart journal, 14 2 2024, Pages ehae224 Mitral valve prolapse: arrhythmic risk during pregnancy and postpartum. Sabbag A, Aabel EW, Castrini AI, Siontis KC, Laredo M, Nizard J, Duthoit G, Asirvatham S, Sehrawat O, Kirkels FP, van Rosendael PJ, Beinart R, Acha MR, Peichl P, Lim HS, Sohns C, Martins R, Font J, Truong NNK, Estensen M, Haugaa KH
Background and aims: Arrhythmic mitral valve prolapse (AMVP) is linked to life-threatening ventricular arrhythmias (VAs), and young women are considered at high risk. Cases of AMVP in women with malignant VA during pregnancy have emerged, but the arrhythmic risk during pregnancy is unknown. The authors aimed to describe features of women with high-risk AMVP who developed malignant VA during the perinatal period and to assess if pregnancy and the postpartum period were associated with a higher ri... Abstract
JACC. Cardiovascular imaging, 10 2 2024, Pages S1936-878X(24)00151-7 Left Atrial Improvement in Patients With Secondary Mitral Regurgitation and Heart Failure: The COAPT Trial. Pio SM, Medvedofsky D, Delgado V, Stassen J, Weissman NJ, Grayburn PA, Kar S, Lim DS, Redfors B, Snyder C, Zhou Z, Alu MC, Kapadia SR, Lindenfeld J, Abraham WT, Mack MJ, Asch FM, Stone GW, Bax JJ, COAPT Trial Investigators
Background: Functional mitral regurgitation induces adverse effects on the left ventricle and the left atrium. Left atrial (LA) dilatation and reduced LA strain are associated with poor outcomes in heart failure (HF). Transcatheter edge-to-edge repair (TEER) of the mitral valve reduces heart failure hospitalization (HFH) and all-cause death in selected HF patients. Objectives: The aim of this study was to evaluate the impact of LA strain improvement 6 months after TEER on the outcomes of patient... Abstract
JACC. Cardiovascular imaging, 10 2 2024, Pages S1936-878X(24)00129-3 Diagnostic Value of Aortic Valve Calcification Levels in the Assessment of Low-Gradient Aortic Stenosis. Adrichem R, Hokken TW, Bouwmeester S, Abdelkarim O, Vogel B, Blusztein DI, Veulemans V, Kuneman JH, Geleijnse ML, Verhemel S, Van den Dorpel MMP, Kardys I, Tonino PAL, Chang SM, Faza NN, Jou S, Ueyama HA, Bartkowiak J, Zeus T, Bax JJ, Bertrand PB, Hahn RT, Kodali SK, Lerakis S, Mehran R, Little SH, Houthuizen P, Van Mieghem NM
Background: In patients with low-gradient aortic stenosis (AS) and low transvalvular flow, dobutamine stress echocardiography (DSE) is recommended to determine AS severity, whereas the degree of aortic valve calcification (AVC) supposedly correlates with AS severity according to current European and American guidelines. Objectives: The purpose of this study was to assess the relationship between AVC and AS severity as determined using echocardiography and DSE in patients with aortic valve area Abstract
The American journal of cardiology, 8 2 2024, Pages S0002-9149(24)00356-4 Significant Mitral Regurgitation After Permanent Right Ventricular Pacemaker Implantation: Prognostic Implications. Nabeta T, Galloo X, Tops L, Stassen J, Marsan NA, van der Bijl P, Bax JJ
The underlying mechanisms leading to the development of mitral regurgitation (MR) after right ventricular (RV) pacemaker (PM) implantation and its prognostic value have yet to be fully understood. The purpose of this study was to evaluate the prevalence and clinical variables associated with the development of MR after RV pacing and its association with outcomes. A total of 451 patients (mean age 69 ± 15 years, 61% male) who underwent de novo RV PM implantation were included. The development of... Abstract
European heart journal, 8 2 2024, Pages ehae231 Cardiac biomarkers for diagnosing Takotsubo syndrome. Schweiger V, Di Vece D, Cammann VL, Koleva I, Würdinger M, Gilhofer T, Rajman K, Szawan KA, Niederseer D, Citro R, Vecchione C, Bossone E, Gili S, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Jansen T, D'Ascenzo F, Bruno F, De Filippo O, Stefanini G, Campo G, Wanha W, Roubin SR, Dichtl W, von Lewinski D, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Massoomi M, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Kato K, Ishibashi I, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguy
JACC. Cardiovascular interventions, 7 1 2024, Pages S1936-8798(24)00692-7 Prognostic Implications of Residual Tricuspid Regurgitation Grading After Transcatheter Tricuspid Valve Repair. Dreyfus J, Taramasso M, Kresoja KP, Omran H, Iliadis C, Russo G, Weber M, Nombela-Franco L, Estevez Loureiro R, Hausleiter J, Latib A, Stolz L, Praz F, Windecker S, Zamorano JL, von Bardeleben RS, Tang GHL, Hahn R, Lubos E, Webb J, Schofer J, Fam N, Lauten A, Pedrazzini G, Rodés-Cabau J, Nejjari M, Badano L, Alessandrini H, Himbert D, Sievert H, Piayda K, Donal E, Modine T, Nickenig G, Pfister R, Rudolph V, Bernick J, Wells GA, Bax J, Lurz P, Enriquez-Sarano M, Maisano F, Messika-Zeitoun D, TRIGISTRY Investigators
Background: The safety profile of transcatheter tricuspid valve (TTV) repair techniques is well established, but residual tricuspid regurgitation (TR) remains a concern. Objectives: The authors sought to assess the impact of residual TR severity post-TTV repair on survival. Methods: We evaluated the survival rate at 2 years of 613 patients with severe isolated functional TR who underwent TTV repair in TRIGISTRY according to the severity of residual TR at discharge using a 3-grade (mild, moderate... Abstract
European heart journal. Cardiovascular Imaging, 6 1 2024, Pages jeae121 Structural and functional abnormalities of left-sided cardiac chambers in Barlow's disease without significant mitral regurgitation. Meucci MC, Mantegazza V, Wu HW, van Wijngaarden AL, Garlaschè A, Tamborini G, Pepi M, Bax JJ, Ajmone Marsan N
Aims: To explore the presence of left ventricular (LV) and left atrial (LA) morphological and functional abnormalities in patients with Barlow's disease (BD) without significant mitral regurgitation (MR) and to investigate whether these abnormalities may predict MR progression. Methods and results: Consecutive patients with BD were retrospectively identified from two tertiary centers; those with MR graded from trivial to mild-to-moderate were selected and matched with healthy controls in a... Abstract
Trials, Volume 25, Issue 1, 6 1 2024, Pages 303 Refraining from closed reduction of displaced distal radius fractures in the emergency department-in short: the RECORDED trial. Derksen BM, Jawahier PA, Wijers O, Knops SP, de Vries MR, van Hooff CCD, Verhofstad MHJ, Schep NWL
Background: With roughly 45,000 adult patients each year, distal radius fractures are one of the most common fractures in the emergency department. Approximately 60% of all these fractures are displaced and require surgery. The current guidelines advise to perform closed reduction of these fractures awaiting surgery, as it may lead to post-reduction pain relief and release tension of the surrounding neurovascular structures. Recent studies have shown that successful reduction does not warrant co... Abstract
Aorta (Stamford, Conn.), 2 1 2024 The Prevalence of Coronary Artery Disease in Bicuspid Aortic Valve Patients: An Overview of the Literature. Dolmaci OB, Hilhorst TL, Malekzadeh A, Mertens BJA, Klautz RJM, Poelmann RE, Grewal N
The prevalence of coronary artery disease (CAD) in bicuspid aortic valve (BAV) patients is a debatable topic. Several studies have indicated that BAV patients have a lower prevalence of CAD compared with patients with a tricuspid aortic valve (TAV), but the effects of age and gender have not always been considered. This systematic review provides an overview of articles which report on CAD in BAV and TAV patients. Searches were executed in April 2021 and January 2022 according to the PRISMA (Pre... Abstract
International journal of cardiology. Heart & vasculature, Volume 52, 2 1 2024, Pages 101418 Coronary calcifications as assessed on routine non-gated chest CT; a gatekeeper to tailor downstream additional imaging in patients with stable chest pain. Groen RA, van Dijkman PRM, Jukema JW, Bax JJ, Lamb HJ, de Graaf MA
Background and aims: Currently applied methods for risk-assessment in coronary artery disease (CAD) often overestimate patients' risk for obstructive CAD. To enhance risk estimation, assessment of coronary artery calcium (CAC) can be applied. In 10 % of patients presenting with stable chest pain a previous non-gated computed tomography (CT) has been performed, suitable for CAC-assessment. This study is the first to investigate the clinical utility of CAC-assessment on non-gated CT for risk-... Abstract